Probably the most frustrating problem with Visual Studio .NET 2003 is that it doesn’t keep the build configuration setting properly.  It’s probably that I am not checking the proper files into source control or something like that.  It is so frustrating and embarrassing when you have changed code and hit F5 and the problem is not fixed.  Then you add a break point and figure out that the project is not even being built!  Hopefully, MSbuild will fix some of these problems.  Currently I use a large solution (150 projects) which include enterprise template projects.  I do some things in post build events and it is annoying that the post build steps are run every time I debug!  Even when nothing is built!  Then of course the build fails because the post build script failed.  This is because some files might have been in use and couldn’t be copied in the post build event.  MSBuild can’t come fast enough!